Comparing Approaches to Treatment Effect Estimation for Subgroups in Clinical Trials
نویسندگان
چکیده
منابع مشابه
Strategies for identifying predictive biomarkers and subgroups with enhanced treatment effect in clinical trials using SIDES.
Several approaches to identification of predictive biomarkers and subgroups of patients with enhanced treatment effect have been proposed in the literature. The SIDES method introduced in Lipkovich et al. (2011) adopts a recursive partitioning algorithm for screening treatment-by-biomarker interactions. This article introduces an improved biomarker discovery/subgroup search method (SIDEScreen)....
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ژورنال
عنوان ژورنال: Statistics in Biopharmaceutical Research
سال: 2017
ISSN: 1946-6315
DOI: 10.1080/19466315.2016.1251490